We cross scientific bridges by connecting biomedical engineers, basic researchers and clinicians with diverse scientific backgrounds. Through the integration of biomedical engineering, chemistry, imaging, immunology and medicine, we develop and advance novel immunotherapy concepts and translate them to the clinic through entrepreneurship.
Prosaposin mediates inflammation in atherosclerosis
Click to readMultimodal imaging of bacterial-host interface in mice and piglets with Staphylococcus aureus endocarditis
Click to readImaging-assisted nanoimmunotherapy for atherosclerosis in multiple species
Click to readEfficacy and safety assessment of a TRAF6- targeted nanoimmunotherapy in atherosclerotic mice and non-human primates
Click to readHigh-Density Lipoprotein Nanobiologics for Precision Medicine
Click to readTherapeutic targeting of trained immunity
Click to readSmart cancer nanomedicine
Click to readProbing myeloid cell dynamics in ischaemic heart disease by nanotracer hot-spot imaging
Click to readNanoengineering Apolipoprotein A1-Based Immunotherapeutics
Click to readInhibiting Inflammation with Myeloid Cell-Specific Nanobiologics Promotes Organ Transplant Acceptance
Click to readTrained Immunity-Promoting Nanobiologic Therapy Suppresses Tumor Growth and Potentiates Checkpoint Inhibition
Click to readOur immune system has evolved to fight off a variety of threats, including infectious diseases and cancer. Unfortunately, these threats are not always properly tackled and diseases develop. We produce, evaluate and translate innovative nanoimmunotherapy and precision imaging approaches for the treatment and diagnosis of cardiovascular and infectious diseases, cancer and transplantation.
The MulderLab consists of two teams spanning two institutions in the south of the Netherlands, namely the Radboud University Medical Center and the Eindhoven University of Technology. We are involved and maintain many formal collaborations, most notably with Mount Sinai’s Biomedical Engineering and Imaging Institute and its Nanomedicine Lab, which Willem Mulder founded in 2006 and directed until December 2020.
